Feder Family:

Adam Sandler as Leonard "Lenny" Feder

Salma Hayek as Roxanne Chase-Feder

Jake Goldberg as Gregory "Greg" Feder

Cameron Boyce as Keith "Keithie" Feder

Sabrina Carpenter as Loretta "Lori" Feder

Alexys Nycole Sanchez as Becky Feder

Lamonsoff Family:

Kevin James as Eric Lamonsoff

Maria Bello as Sally Lamonsoff

Leo Howard as Ethan Lamonsoff

Ada-Nicole Sanger as Donna Lamonsoff

Frank Gingerich and Morgan Gingerich as Bean Lamonsoff

McKenzie Family:

Chris Rock as Kurt McKenzie

Maya Rudolph as Deanne McKenzie

China Anne McClain as Charlotte McKenzie

Tyrel Jackson Williams as Chase McKenzie

Nadji Jeter as Andre McKenzie

Hilliard Family:

Rob Schneider as Rob Hilliard

Joyce Van Patten as Gloria Noonan-Hilliard

Madison Riley as Jasmine Hilliard

Jamie Chung as Amber Hilliard

Ashley Loren as Bridget Hilliard

Corey Fogelmanis as Roland Hilliard

Higgins Family:

David Spade as Marcus Higgins

Owen Wilson as Oliver Higgins

Kate Beckinsale as Melissa Higgins

Patrick Warburton as Austin Higgins

Dove Cameron as Amelia Higgins

Skyler Gisondo as Brian Higgins

Zachary Gordon as Seth Higgins

Peyton List (1998) as Monica Higgins

The rest of the cast as themselves.