The osler medical handbook -john hopkin
Section VIII – Infectious DiseasesSection Editors:Christopher Hoffmann, MD, MPH Nicola Zetola, MDChapter 53 – Fever of Unknown OriginScott Kim, MD Rachel Damico, MD, PhD Paul Auwaerter, MDFAST FACTS ▪ The contemporary understanding of fever of unknown origin (FUO) is derived from Petersdorf and Beeson's 1961 characterization of FUO. A stringent definition of FUO is composed of the following criteria[1]: temperature higher than 38.3° C measured on several occasions, 3-week duration (to exclude self-limiting fevers), negative blood cultures, no apparent explanation, and three outpatient visits or three hospital days. ▪ Infections, malignancies, and noninfectious inflammatory diseases account for the majority of cases of FUO. ▪ In patients older than 65 years, temporal arteritis should be considered early in any evaluation. ▪ Patients with FUO who remain undiagnosed after exhaustive study usually have a favorable prognosis. In one study, in a cohort of 61 patients with FUO discharged without diagnosis, the 5-year mortality rate was only 3.2%.[2]…


![[Full] Cô Vợ Tái Sinh 1](https://truyen2u.com/images/full-co-vo-tai-sinh-1-338603256.webp)

![[ORV] Buried alive and still breathing](https://truyen2u.com/images/orv-buried-alive-and-still-breathing-346650304.webp)

![[BHTT - Kiều Lan] Chị trợ lý của](https://truyen2u.com/images/bhtt-kieu-lan-chi-tro-ly-cua-anh-224962917.webp)

![[ TNT_Thời Đại Thiếu Niên Đoàn ] Tổng hợp oneshot](https://truyen2u.com/images/tnt-thoi-dai-thieu-nien-doan-tong-hop-oneshot-294035984.webp)






![[REUP] Thi Đại Học Toàn Cầu - Mộc Tô Lý](https://truyen2u.com/images/reup-thi-dai-hoc-toan-cau-moc-to-ly-297904717.webp)
